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"How Do I Shot Web?" is a popular catchphrase paired with an image of Spider-man, that is typically used in online conversations to poke fun at n00bish behavior.
The OG comic panel was made in 1984 for a issue of The Amazing Spiderman.
This grammatically strange phrase initially spread as an in-joke among SomethingAwful users who frequented the FYAD ("Fuck You and Die") section, where an image macro of Spider-Man saying the phrase spawned hundreds of other pictures containing the phrase.